Lecturer Patrice Castignolles

• Biography Areas of Research / Teaching Expertise
• Grants / Current Projects
• Awards and Recognition
• Selected Publications
• Optional
• Contact Details

Biography

I have made significant contributions to the understanding of polymerization kinetics and the separation and characterization of polymers, especially branched polymers, polyelectrolytes and polysaccharides.
Using a combination of theory, simulation and experiment, I showed that certain reactions (viz., transfer) with dead polymer chains play a major role in the polymerization of alkyl acrylates, widely used industrially (in adhesives, coatings and paints). It was published in several seminal papers, including one on benchmark rate coefficients, under the auspices of IUPAC.
I have made important contributions to the understanding of the separation of polymers by liquid chromatography (particularly size-exclusion chromatography, SEC). I showed that SEC is generally applied in a limited and often also incorrect way. I showed how these problems could be corrected by proper use of apparent molar masses determined by SEC in controlled/living polymerization. I derived the first rigorous expression for the signals of multiple detectors in SEC, and showed how such data can be processed correctly for complex polymers. I have recently applied this theory to the first accurate characterization of branched poly(alkyl acrylates), branched glucans and copolymers of methacrylic acid and methyl methacrylate, studies which give considerable insight into the (bio)syntheses of these important classes of polymers.

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Areas of Research / Teaching Expertise

Polymer Science; Separation Science; Analytical Chemistry; Materials Science; Food Science; Size-exclusion chromatography (SEC/GPC); capillary electrophoresis

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Grants / Current Projects

Separation and characterization of (natural) polymers and their architecture by liquid chromatography and electrophoresis

2010 College Equipment Grant from UWS with Dr Sundar Koyyalamudi and Dr Marion Gaborieau: Capillary Electrophoresis
2008 Discovery Project from the ARC with Pr. MJ Gidley, Pr. RG Gilbert: Establishing the relations between starch nano- and mesostructure and macroscopic physical properties
2008 Early-career research grant from UQ: Novel methods for the characterization of complex polyelectrolytes: hydrophilic polyacrylates
2007 Start-up grant from the University of Queensland: Characterization of complex branched polyacrylates

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Awards and Recognition

2010-: Member of the Scientific committee of the “international symposium on separation and characterization of synthetic and natural macromolecules”, SCM
2008 Invited lecturer (1 month) by Pr. Denis Bertin, University of Provence (Marseilles)
2005: International linkage fellowship from the ARC: Branching in acrylic polymers: analysis and mechanistic understanding
2003: Ph.D. in chemistry and physics of polymers, University of Paris VI, France, with honors:
Free-radical polymerization kinetics: acrylate monomers studied by PLP (pulsed laser polymerization) coupled to multiple-detection SEC (size-exclusion chromatography)
2000: Masters degree in chemistry and physics of polymers, University of Paris VI, with honors:

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Selected Publications

Researcher ID: http://www.researcherid.com/rid/C-1399-2008
Selected Publications (# is the corresponding author, ranking according to ERA in bold blue, non-self citations according to SciFinder on 7 March 2011):
1. Size-exclusion chromatography (SEC) of branched polymers and polysaccharides,
P Castignolles#, M Gaborieau,
Analytical & Bioanalytical Chemistry (B), 399, 1413-1423 (2011) review
invited by Prof. A. Striegel http://dx.doi.org/10.1007/s00216-010-4221-7
2. Polymerization kinetics: monitoring monomer conversion using an internal standard – key Role of sample t0
O Colombani#, P Castignolles, O Langelier, E Martwong
Journal of Chemical Education (B), 88, 116-121 (2011) http://dx.doi.org/10.1021/ed100404r
3. Determination of Propagation Rate Coefficients for Methyl and 2-Ethylhexyl Acrylate via High Frequency PLP-SEC under Consideration of the Impact of Chain Branching
T Junkers#, P Castignolles, C Barner-Kowollik,
Macromolecules (A*), 43, 10427-10434 (2010) http://dx.doi.org/10.1021/ma102130h
4. Viscosimetric detection in size-exclusion chromatography (SEC/GPC):the Goldwasser method and beyond
M Gaborieau, P Castignolles#,
Journal of Separation Science (B), 33, 3564-3570 (2010),
Invited by Dr HJ Cortes and Prof L Mondello for a special issue on “Separation science and macromolecular characterization” http://dx.doi.org/10.1002/jssc.201000511
5. Reducing the Degree of Branching in Polyacrylates via Mid-Chain Radical Patching: A Quantitative Melt-State NMR Study
M Gaborieau#, SPS Koo, P Castignolles, T Junkers#, C Barner-Kowollik#,
Macromolecules (A*), 43, 5492-5495 (2010), http://dx.doi.org/10.1021/ma100991c
6. Molecular weight and tacticity of oligoacrylates by capillary electrophoresis – mass spectrometry
M Gaborieau, TJ Causon, Y Guillaneuf, EF Hilder, P Castignolles#
Australian Journal of Chemistry (B), 63, 1219-1226 (2010),
invited by Prof Martina Stenzel for a special issue about the Polymer Pacific Conference,
1 non-self citation http://dx.doi.org/10.1071/CH10088
7. Transfer to polymer and long-chain branching in PLP-SEC of acrylates
P Castignolles#
Macromolecular Rapid Communications (A), 23, 1995-2001 (2009)
invited by Pr. Christopher Barner-Kowollik for a special issue about “acrylate free radical polymerization”, 3 non-self citations http://dx.doi.org/10.1002/marc.200900530
9. Caractérisation de l’amidon et de ses matériaux composites
P Castignolles, M Gaborieau# invited by JC Daniel
Annales des Falsifications, de l'expertise chimique & toxicologique, 971, 23-31 (2009)
http://chimie-experts.org/pdf/Sommaire-971.pdf
10. Detection and quantification of branching in polyacrylates by size-exclusion chromatography (SEC) and melt-state 13C NMR spectroscopy
P Castignolles, R Graf, M Parkinson, M Wilhelm, M Gaborieau#
Polymer (A), 50, 2373-2383 (2009)
12 non-self citations http://dx.doi.org/10.1016/j.polymer.2009.03.021
13. Assessment of the extent of starch dissolution in dimethylsulfoxide by 1H NMR spectroscopy,
S Schmitz, AC Dona, P Castignolles, RG Gilbert, M Gaborieau#,
Macromolecular Bioscience (B), 9, 506-514 (2009)
10 non-self citations http://dx.doi.org/10.1002/mabi.200800244
14. * Toward a full characterization of native starch: separation and detection by size-exclusion chromatography,
NL Hoang, A Landolfi, A Kravchuk, E Girard, J Peate, JM Hernandez, M Gaborieau, O Kravchuk, RG Gilbert, Y Guillaneuf, P Castignolles#,
Journal of Chromatography A (A*), 1205, 60-70 (2008)
7 non-self citations http://dx.doi.org/10.1016/j.chroma.2008.07.090
15. Separation of complex branched polymers by size-exclusion chromatography (SEC) probed with multiple detection,
M Gaborieau, J Nicolas, M Save, B Charleux, J-P Vairon, RG Gilbert, P Castignolles#,
Journal of Chromatography A (A*), 1190, 215-223 (2008)
15 non-self citations http://dx.doi.org/10.1016/j.chroma.2008.03.031
16. Mechanistic investigation of a starch branching enzyme using hydrodynamic volume SEC analysis,
JM Hernandez, M Gaborieau, P Castignolles, MJ Gidley, AM Myers, RG Gilbert#,
Biomacromolecules (A), 9, 954-965 (2008)
7 non-self citations http://dx.doi.org/10.1021/bm701213p
17. Synthesis of methacrylate derivative oligomers by dithiobenzoate-RAFT mediated polymerization,
E Hosseini Nejad, P Castignolles, RG Gilbert, Y Guillaneuf#,
Journal of Polymer Science, Part A: Polymer Chemistry (A), 46, 2277-2289 (2008)
2 non-self citations http://dx.doi.org/10.1002/pola.22563
19. Using apparent molecular weight from SEC in controlled /living polymerization and kinetics of polymerization,
Y Guillaneuf, P Castignolles#,
Journal of Polymer Science, Part A: Polymer Chemistry (A), 46, 897-911 (2008)
15 non-self citations http://dx.doi.org/10.1002/pola.22433
23. Towards a more general solution to the band-broadening problem in size separation of polymers
D Konkolewicz, JW Taylor, P Castignolles, A Gray-Weale, RG Gilbert#,
Macromolecules (A*), 40, 3477-3487 (2007)
11 non-self citations http://dx.doi.org/2010.1021/ma062973a
24. Theory of multiple detection of size exclusion chromatography of complex branched polymers
M Gaborieau, JM Hernandez, RG Gilbert, A Gray-Weale, P Castignolles#,
Macromolecular Theory and Simulations (C), 16, 13-28 (2007)
24 non-self citations http://dx.doi.org/10.1002/mats.200600046
25. Structural and thermal properties of PMMA/Zinc Oxide nanocomposites by in situ polymerization,
MM Demir, M Demesa, P Castignolles, G Wegner#,
Macromolecular Rapid Communications (A), 27, 763-770 (2006)
40 non-self citations http://dx.doi.org/2010.1002/marc.200500870
26. High-resolution separation of oligo(acrylic acid) by capillary zone electrophoresis,
P Castignolles#, M Gaborieau, EF Hilder, E Sprong, CJ Ferguson, RG Gilbert,
Macromolecular Rapid Communications (A), 27, 42-46 (2006)
3 non-self citations http://dx.doi.org/10.1002/marc.200500641
28. New experimental procedure to determine the recombination rate constants between nitroxides and macroradicals,
Y Guillaneuf, D Bertin#, P Castignolles, B Charleux#,
Macromolecules (A*), 38, 4638-4646 (2005)
16 non-self citations http://dx.doi.org/2010.1021/ma050241x
29. Critically evaluated rate coefficients for free-radical polymerization, 5, Propagation rate coefficient for butyl acrylate,
JM Asua, S Beuermann, M Buback, P Castignolles, B Charleux, RG Gilbert, RA Hutchinson#, JR Leiza, AN Nikitin, J-P Vairon, AM van Herk,
Macromolecular Chemistry Physics (B), 2004, 16, 2151-2160
127 non-self citations http://dx.doi.org/2010.1002/macp.200400355
30. Determination of propagation rate coefficients of acrylates by pulsed-laser polymerization in the presence of intramolecular transfer to polymer,
AN Nikitin, P Castignolles, B Charleux#, J-P Vairon,
Macromolecular Rapid Communications (A), 2003, 24, 778-782
35 non-self citations http://dx.doi.org/10.1002/marc.200350025

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Optional

Collaborations:

Dr Marianne Gaborieau, UWS: structure and dissolution of branched polyacrylates, starch and chitosan.
Dr Antonio Lauto, UWS: chitosan for biomedical applications
Prof Manfred Schmidt, University of Mainz, Germany, Capillary electrophoresis (CE) of polyelectrolytes and polyelectrolytes complexes
Dr Emily Hilder, University of Tasmania, ACROSS: separation by CE and CE-MS,
Dr Catherine Lefay, Prof Denis Bertin, University of Provence, France, chitosan conjugates
Dr Yohann Guillaneuf, Dr Didier Gigmes, University of Provence, France, (hyper)branched polymers for drug delivery and apparent molecular weight in SEC
Dr Anatoly Nikitin, Institute of Lasers, Shatura, Russia, PLP-SEC of acrylates
Prof Marc in het Panhuis, University of Wollongong, CE of functional polysaccharides
Prof Mathias Destarac, University Paul Sabatie, Toulouse, France, CE of double-hydrophilic block copolymers
Dr Francois Ganachaud, Ingenerie et Architectures Macromoleculeculaires, Montpellier, France, CE of supramolecular assemblies
Professional societies and engagement :

Member of the Royal Australian Chemical Institute (RACI, 2005), member of the standing committee of the RACI Polymer Division and of the Queensland Polymer Group (2007), secretary of the RACI NSW Polymer Group. Organization of the workshop “Polymeric materials and polysaccharides” in November 2010 (65 participants).
Member of the French polymer group (GFP, since 2001),
Member of the French chemical society (SCF, since 2006), the American Chemical Society (ACS, 2008), the German chemical society (GDCh, 2008),
Member of the elite IUPAC working party on “kinetics of polymerization” (chair: Dr. Greg Russell, greg.russell@canterbury.ac.nz) since 2004

Visit Doctor Patrice Castignolles' website

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