Students studying at Hawkesbury or Parramatta campus should refer to 300220 - Biochemistry 2. Understanding human metabolism at a molecular level underpins our understanding of human health and metabolic diseases, such as diabetes and obesity. Kinetics and regulation of enzymes will be studied as a preliminary to learning how metabolic pathways work. The central pathways of energy metabolism, their control and inter-relationships will be analysed in detail, including carbohydrate and fat metabolism; ATP synthesis involving electron transport and ATP synthase; and nitrogen metabolism, including aspects of amino acid degradation and urea synthesis. Emphasis will be placed on enzyme and hormonal regulations, the roles of different tissues in metabolic homeostasis; and the consequences for human health when enzymes or their regulations are defective.

Students studying at Hawkesbury or Parramatta campus should refer to 300301 - Organic Chemistry 2. This unit introduces organic chemistry from a biological and pharmaceutical perspective, emphasising the structure & reactivity of biological molecules as organic molecules and functional group manipulation as a tool for drug design and synthesis. Appropriate practical skills to achieve this are learnt in the associated practical work.

This unit will aim to develop within the student an understanding of, and an appreciation for, the fundamentals of analytical chemistry. The student will be exposed to the theory and practice of a range of chemical analyses with emphasis on ‘wet’ or ‘classical’ methods, and an introduction to some instrumental methods. An important component of this unit is to develop within the student laboratory skills in chemical analysis. Topics covered in this unit include: the evaluation of analytical data; sampling and sample preparation; unit operations in analytical chemistry; stoichiometry and equilibrium; gravimetric analysis; volumetric analysis; separation methods; spectroscopic methods of analysis; electrochemical methods of analysis; analysis of real samples.

Students studying atParramatta campus should refer to 300230 - Inorganic Chemistry 2. This unit introduces students to a thorough study of coordination chemistry (discussing complexes, ligands, structure, isomerism, stability, reaction mechanisms, oxidation states, elements in the first transition series, and trends in the periodic table). That foundation is then used to study applications of coordination chemistry in biological systems, in medicine and in areas such as radiopharmaceuticals. The unit then moves on to areas of fundamental inorganic chemistry, including bonding, solution chemistry, and solid state chemistry. This unit also introduces many of the laboratory techniques and equipment that are used in synthetic procedures in coordination chemistry.

Students studying at Parramatta campus should refer to 300236 - Physical Chemistry 2. The unit provides the understanding of the chemical principles as applied to biological molecules (biomolecules). Chemical and electrochemical energy transformations approaching equilibria and rates of biological processes are studied and further explored for useful experimental and data-analysis skills. Selected areas including enzyme kinetics or membrane equilibria will be studied.

Students studying at Hawkesbury or Parramatta campus should refer to 300235 - Organic Chemistry 3. This unit introduces selected areas of more advanced organic chemistry, targeted largely on the tools to synthesise and identify organic molecules of biological and medicinal interest. The practical skills required are learnt through laboratory exercises which complement the theory.

Students studying at Hawkesbury or Parramatta campus should refer to 300298 - Analytical Chemistry 3. This unit provides the student with skills to carry out the more advanced wet chemical analysis and provides an understanding of the principles of instrumental analysis, covering the areas of spectroscopy, chromatography, electrochemistry, thermal methods and automated methods of analysis. The techniques of analytical method development, inorganic and organic residue analysis, herbal analysis and forensic toxicology analysis will be discussed. Aspects of quality control and quality assurance will also be included.

Contemporary medicinal chemistry relies upon a rigorously planned and rational design of drugs based upon a full understanding of both chemistry and biology. An ability to determine and define the chemical structure of the drug, its target system, its site of action and its destruction mechanisms, has allowed the scientist to systematically tailor a drug to its specific purpose using quantitative structure-activity relationships (QSAR) and this methodology is emphasised within the unit. With the accelerating development of computer-based technologies this capability has been extended further. Drugs such as cimetidine and other histamine antagonists are used to illustrate the achievement and future uses of structure-activity relationships in rational drug design, whilst the laboratory work leads to a simulated quantitative structure-activity determination relating to antimicrobials.

Students studying at Hawkesbury or Parramatta campus should refer to 300231 - Inorganic Chemistry 3. Advanced Inorganic Chemistry is based on the foundations laid in the unit Coordination Chemistry. It covers structure and bonding in inorganic chemistry, higher coordination numbers, lanthanide and actinides, followed by the bioinorganic chemistry of zinc and iron in mammalian and microbial systems. Kinetics and mechanism of inorganic reactions are examined. The important area of organo-transition metal chemistry and catalysis is introduced. Students build on their familiarity with the literature of inorganic chemistry and are introduced to several advanced databases of chemical information. The laboratory sessions develop knowledge of advanced techniques such as anaerobic syntheses and instrumental techniques of characterisation such as NMR, IR and electronic spectra. This is also used to develop an appreciation of the role of computer-based molecular modelling in inorganic chemistry.

This unit investigates the mechanisms and pathways of degradation of introduced compounds within the body and of their removal from the body; the relationship between chemical structure and stability of compounds within the body, including quantitative structure-stability relationships; the physical, metabolic and chemical stability within the body of representatives of each of the major types of drug class, relating this stability to molecular structure; the influence of the stability of drug compounds within the body upon the choice of drug delivery system used.